Clinical Trial: Cannabis Extracts Significantly Reduce Myofascial Pain

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Apple is slowly releasing the details of new products this week. Monday already brought the news of the iPhone 17e, a budget-friendly offering starting at $599. It also announced a new M4 iPad Air, which starts at $599. Pre-orders for the devices begin on Wednesday, March 4.

both of these approaches use NFAs under the hood, which means O(m * n) matching. our approach is fundamentally different: we encode lookaround information directly in the automaton via derivatives, which gives us O(n) matching with a small constant. the trade-off is that we restrict lookarounds to a normalized form (?<=R1)R2(?=R3) where R1/R2/R3 themselves don’t contain lookarounds. the oracle-based approaches support more general nesting, but pay for it in the matching loop. one open question i have is how they handle memory for the oracle table - if you read a gigabyte of text, do you keep a gigabyte-sized table in memory for each lookaround in the pattern?

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Речь идет о генетически измененных макрофагах — клетках иммунной системы, которые в норме могут пересекать гематоэнцефалический барьер. Исследователи снабдили их химерным антигенным рецептором (CAR), нацеленным на белок мезотелин, характерный для ряда опухолей, включая рак легких, молочной железы и меланому. Дополнительно в конструкцию встроили сигнальную молекулу MyD88, усиливающую противоопухолевую активность клеток. Полученные клетки назвали CARMA.